Vascular compression of the trigeminal nerve can be treated with medication and surgery such as trigeminal nerve microvascular decompression and trigeminal nerve sensory rhizotomy. 1. Drug treatment: vascular compression of trigeminal nerve can lead to trigeminal neuralgia, which can be treated with carbamazepine, gabapentin, pregabalin and other drugs. 2. Surgery: those who are not well controlled by medication can choose surgery, such as trigeminal nerve microvascular decompression, i.e., open the small bone window behind the ear, look for the compression of trigeminal blood vessels, and use cotton wool to isolate them, with a high cure rate. Trigeminal sensory rhizotomy can also be done, which can also achieve the goal of eradication and has low surgical risk. It is up to the doctor to evaluate which treatment to choose, so it is recommended to visit the hospital in time for early and regular treatment.