Two and a half year old baby with a fever of 39 ℃, need general treatment and drug treatment. 1. General treatment: mainly to physical cooling. Babies with high fever need to reduce clothing, avoid covering quilts, while the whole body warm water bath, if necessary, can be warm water bath. At the same time, the head and the whole body can be paste antipyretic paste to help reduce fever. 2. Medication: For high fever above 38.5℃, you need to take oral ibuprofen or acetaminophen suspension to reduce fever. If it is a bacterial infection, you can take oral cefaclor and other antibacterial treatment; mycoplasma infection, with azithromycin anti-infective treatment and so on. Two and a half year old baby fever 39 ℃, the cause is very much, it is recommended that timely medical care, identify the cause, as soon as possible to receive treatment, the above medication need to comply with medical advice.