A crooked mouth and watery eyes may be due to facial paralysis or neuropathy in the brain, and the specific causes should be reasonably determined under the guidance of a doctor. 1. Facial paralysis: some patients may develop facial paralysis after viral infection, which may lead to watery mouth and eyes. It can be relieved by taking oral nerve-nourishing drugs, such as methylcobalamin, or with hormone therapy, such as prednisone. Besides, it can also be relieved with acupuncture and massage. 2. Neuropathy of the brain: when the patient’s brain nerve damage occurs, it may stimulate the muscles of the face, muscle contraction may cause crooked mouth and tearing eyes, you can take vitamin B12 and other drugs to improve the situation. Crooked mouth, tearing eyes, we should go to the regular hospital for relevant examination, clear specific reasons for active treatment, to avoid serious consequences.