Whether the endometrium is 15 cm thick and can be recovered without scraping is clinically dependent on the age of the patient and the ancillary tests. In the case of women over 40 years of age with an endometrial thickness of 15 cm, curettage is required because there is a possibility that it may turn malignant and cancerous, and pathological tests should be done on the scraped tissue. After the pathology test, we can determine the cause of the thickened lining and treat it promptly. If the endometrial thickening is 15 cm thick in adolescent women, it can be treated without scraping because the possibility of cancer at this age is relatively small, and relevant clinical examination and treatment with oral medication or estrogen supplementation can achieve the ideal treatment effect. Regardless of the age of women, endometrial thickening is a pathological reaction and requires targeted treatment.