Colchicine tablets should not be taken by pregnant and lactating women, hypomelanosis, and patients with hepatic or renal insufficiency. Colchicine is mainly used for the treatment of acute attacks of gouty arthritis and the prevention of acute attacks of recurrent gouty arthritis. Colchicine has a risk of teratogenicity, so pregnant and lactating women should not take colchicine orally. Colchicine also has significant myelosuppressive side effects, such as leukopenia, anemia, and low platelet counts, so it should not be used in patients with myelodysplasia. The side effects of colchicine are relatively large, and can cause liver and kidney damage. Patients with liver and kidney insufficiency can cause the drug to accumulate in the body, which will aggravate the damage of liver and kidney function, so patients with liver and kidney insufficiency should not take colchicine. Colchicine should be used under the guidance of a professional doctor, do not take it privately or increase or decrease the dosage, the use of the process must be followed up regularly, the emergence of adverse reactions immediately stop the drug, and promptly consult a doctor.