Patients with severe varicocele on the left side may suffer from heavy scrotum, cramping pain, pain in the left groin and perineum, and even lead to male infertility and testicular atrophy. Common treatments include medication, surgery, etc., which should be carried out according to the doctor’s prescription. Patients with severe varicocele on the left side are mainly treated by surgery, supplemented by medication. 1. Medication: For patients with localized pain in the scrotum, non-steroidal anti-inflammatory drugs such as ibuprofen can be used for treatment. For patients with combined sperm abnormalities, gonadotropins, clomiphene, vitamin E and other drugs can be used to improve the quality of semen. 2. Surgical treatment: The main purpose is to improve the patient’s discomfort and restore fertility. Commonly used surgical treatments include transperitoneal laparoscopic spermatic vein ligation and spermatic vein embolization. Patients with severe varicocele on the left side should seek timely medical treatment and therapy, and use medication reasonably under the guidance of the doctor, and should not abuse the medication on their own. Meanwhile, they should wear loose clothes and pants in daily life and avoid standing or walking for a long time, so as not to increase the abdominal pressure, scrotal pulling and aggravate the disease.