Endoscopic treatment of esophagitis mainly involves endoscopic repair and removal of localized ulcerated surfaces, with possible sequelae such as esophageal bleeding, esophageal stricture, esophageal perforation, and anastomotic fistula. 1. Esophageal bleeding: it can be divided into intraoperative bleeding and postoperative delayed bleeding. Postoperative hemorrhage is the symptoms such as vomiting blood, black stool and panic when the patient returns home or ward after endoscopic surgery. At this time, the patient’s condition should be closely observed and hemostasis should be carried out again under endoscopy in a timely manner. 2. Esophageal stenosis: after endoscopic repair and removal of the ulcerated surface, scar tissue will gradually form on the traumatic surface of the esophagus, which may cause esophageal stenosis or contracture, leading to symptoms such as difficulty in swallowing. 3. Esophageal perforation: it is divided into intraoperative perforation and postoperative perforation. Intraoperative perforation can be closed endoscopically with titanium or metal clips; postoperative perforation may be combined with peritonitis, and after ineffective drug treatment, a second surgery can be considered to repair the perforation. 4. Anastomotic fistula: the main manifestation of the anastomotic site of incomplete anastomosis or anastomosis due to malnutrition and other factors can not be normal growth, so that the esophageal contents into the chest cavity. Endoscopic treatment of esophagitis may also have sequelae such as esophageal incision infection. It is recommended to seek medical treatment in time, under the guidance of the doctor for targeted treatment.