Hepatitis B dna quantification itself does not cause elevated alpha-fetoprotein, but when there is liver cell destruction, alpha-fetoprotein will be elevated, and elevated alpha-fetoprotein is also related to malignant tumors. If hepatitis B dna quantification is greater than normal, it means that there is more hepatitis B virus in the body and there exists the state of active replication, but the liver function is not necessarily abnormal, and there is not necessarily the destruction of liver cells. When there is the destruction of liver cells, alpha-fetoprotein and other liver enzymes will be released into the bloodstream, which will cause the elevation of alpha-fetoprotein and the abnormality of liver function. Especially when hepatitis B enters the stage of cirrhosis, it is necessary to be alert to the elevation of alpha-fetoprotein, and it is necessary to consult a doctor in time to improve the ultrasound of the liver, CT scan and other examinations to clarify whether there is hepatocellular carcinoma or not. Elevated alpha-fetoprotein is also related to malignant tumors in other organs, such as gastric cancer with liver metastasis, teratocarcinoma, colon cancer, gastric cancer, pancreatic cancer, ovarian cancer, testicular tumors and so on. Therefore, when hepatitis B patients find elevated alpha-fetoprotein, it is recommended to consult a doctor in time and give targeted treatment after detailed examination to clarify the cause of the disease.