Foot peeling may be tinea pedis, eczema, contact dermatitis, etc. Different diseases have different causes and different solutions, such as topical or oral medication. 1. Tinea pedis: often caused by fungal infection, can be manifested as erythema, blisters, flaking and so on. Usually, attention should be paid to keep the feet clean and dry. Usually use antifungal drugs externally, such as ketoconazole cream, miconazole cream, etc.; patients with serious symptoms also need to follow the doctor’s advice oral antifungal drugs, such as itraconazole, terbinafine, etc. (oral drugs also need to pay attention to the adverse effects of the drug, such as liver function abnormalities, etc.). 2. Eczema: the disease is an internal and external factors lead to superficial dermis and epidermis inflammatory skin disease, can be manifested as foot erythema, flaking, accompanied by itching. Glucocorticoid drugs can be used externally, such as compound dexamethasone cream, oral antihistamine drugs, such as loratadine, cetirizine, etc.. 3. Contact dermatitis: it is an allergic disease, which can appear in the contact area, such as feet, erythema, papules, blisters and so on, accompanied by itching, and flaking after the blisters dry up. Patients are advised to search for and avoid contact with allergens, use topical glucocorticoid creams, and take oral antihistamines; for patients with severe symptoms, glucocorticosteroids can be applied systematically as prescribed by the doctor and their adverse reactions can be monitored regularly. It is recommended that patients with peeling feet go to regular hospitals in a timely manner, under the guidance of the doctor to do the relevant examinations, after a clear diagnosis and standardized treatment in accordance with the doctor’s instructions.