Chronic hepatitis B virus carriers usually neglect to check because they don’t feel uncomfortable, which is not desirable. “Carrying” is not static, and the apparent calmness is not necessarily the real calmness. The vast majority of chronic hepatitis B in China has evolved from chronic hepatitis B virus carriers. Therefore, it is important to have regular checkups to detect any changes in your condition and seize the best time for treatment. After the hepatitis B virus infects the human body, if the body has strong resistance, normal immune function and timely treatment, the hepatitis B virus will be cleared quickly and hepatitis B can be cured in the acute stage. However, once the hepatitis B virus is not cleared in time, hepatitis B will become chronic and the virus will be carried for a long time, and the test will show that the hepatitis B antigen is positive, i.e. hepatitis B virus carrier. If hepatitis B virus is active in liver cells, replication and reproduction, clinical symptoms can appear. At this time should be timely to the hospital, if delayed treatment, a very small number of patients can develop into severe hepatitis, manifested as liver function damage sharply aggravated until failure, accompanied by renal failure and other multiple organ function damage, the patient will appear continuously aggravated jaundice, oliguria, anuria, ascites, blurred consciousness, coma and so on. Chronic hepatitis B disease for a long time, will be along the “slow hepatitis B – cirrhosis – liver cancer” direction of evolution, that is, we often say “hepatitis B trilogy”. Therefore, chronic hepatitis B virus carriers should not not go to the checkup because they feel fine, “carrying” is not static, the surface is not necessarily calm, must be regular review, seize the opportunity to treat, to stop the progress of the disease.