How malignant lymphoma is treated

  Conventional treatment is as follows: Malignant lymphoma is different from both other solid malignant tumors with lymphatic metastases and hematologic tumors. It includes Hodgkin’s lymphoma and non-Hodgkin’s lymphoma, and the clinical manifestations are intricate and complex depending on the pathological type, stage and invasion site.  In terms of treatment, comprehensive treatment is mostly used at present, that is, according to different tumors, different pathological types and subtypes, different biological behaviors, different disease stages and development tendencies, different behavioral states of the body and important organ functions, various existing treatments are applied in a planned and rational manner, in order to maximize the protection of the body and maximize the killing of tumor cells, so as to achieve the purpose of increasing the cure rate and improving the quality of life. The treatments commonly used for malignant lymphoma include radiation therapy (radiotherapy), chemotherapy (chemotherapy), Chinese herbal medicine, biological response modifiers (BRM), and surgical resection. Chemotherapy combined with radiotherapy has a high cure rate or remission rate for malignant lymphoma, and a small percentage of patients need to undergo surgery.  Radiation therapy (1) Hodgkin’s lymphoma: The effect of radiation therapy is better in early stage patients, and the method of irradiation is “cloak” or inverted “Y” type irradiation field is used more often. Generally, the amount of tissue given is about 4000 cGy in 4 weeks, and important organs are protected during treatment.  (2) Non-Hodgkin’s lymphoma: Non-Hodgkin’s lymphoma is also sensitive to radiotherapy, but the recurrence rate is high. Therefore, only clinical stage I and II in the low malignancy group and pathological stage I in the moderate malignancy group can be treated with radiotherapy alone to expand the field or only to involve the field. The primary lesions of non-Hodgkin’s lymphoma such as in tonsils, nasopharynx or histiocytic type with primary in bone can obtain more satisfactory long-term remission after local radiotherapy.  2.Chemotherapy. Chemotherapy is a very effective treatment for intermediate to advanced Hodgkin’s lymphoma and non-Hodgkin’s lymphoma.  3.Immunotherapy. For malignant lymphoma, immunotherapy can be used as an adjuvant treatment.  4.Autologous bone marrow transplantation. For patients under 50 years of age who can tolerate the combination of high-dose radiotherapy and chemotherapy, combined with allogeneic or autologous bone marrow transplantation, a long remission period and disease-free survival can be expected.  5. Molecular targeted therapy. For CD20-positive lymphoma, treatment with CD20 monoclonal antibody can be added.  6.Surgical treatment. In patients with intra-nodal malignant lymphoma, surgery is mainly used for biopsy for pathology or for staged partial abdominal exploratory surgery. For extra-nodal malignant lymphoma originating in the brain, spinal cord, orbit, salivary gland, thyroid, lung, liver, spleen, etc., surgical resection is often performed first, followed by radiotherapy and/or chemotherapy. Malignant lymphomas originating in the kidney, bladder, testes, ovaries, uterus, skin, breast, etc. should be removed surgically at an early stage and followed by chemotherapy and/or radiotherapy.