It is generally recommended to follow up with Botox injections more than 3 months apart and when similar symptoms recur, but for patients with poorly controlled symptoms or adverse reactions after Botox injections, it is recommended to follow up after 2 weeks. After botulinum toxin injection, a second injection is recommended after three months. However, for patients with poorly controlled symptoms after treatment, a follow-up visit and a second supplemental Botox injection can be given after 2 weeks. Possible adverse reactions after Botox injections include swelling, hematoma, pain at the injection site, mild headache, transient flu-like symptoms, and symptoms due to target muscle weakness. After facial botulinum toxin injections patients may experience adverse reactions such as droopy eyelids, blurred vision, dry eyes, crooked mouth, restricted mouth opening, and facial asymmetry. After botulinum toxin injection in the neck, patients may experience weakness in head lifting and difficulty in swallowing. Patients may experience corresponding limb weakness after botulinum toxin injection in the limbs. All of the above adverse reactions may gradually resolve on their own after 2 to 12 weeks. Since the adverse reactions after botulinum toxin injection can resolve on their own, not all patients with adverse reactions need to return to the hospital for follow-up, but if patients have difficulty swallowing, difficulty breathing, slurred speech, etc., they should return to the hospital in a timely manner. For bruising at the injection site after botulinum toxin injection, ice and hot compresses can be applied. In case of facial adverse reactions such as drooping eyelids and crooked mouth, patients can use cell phones to take pictures and record the daily changes of symptoms. If blurred vision or double vision occurs after injection, patients should be careful to avoid activities such as driving and operating dangerous machines. In the case of poor eye closure and eye dryness after injection, patients can use eye drops such as artificial tears to improve symptoms.