Secondary liver cancer often manifests as discomfort or pain in the upper abdomen, yellowing of the skin and sclera, weight loss, fever, ascites and so on. Secondary liver cancer, also known as metastatic liver cancer, is a tumor formed when malignant tumors from other parts of the body metastasize to the liver. Tumors from all organs of the body can metastasize to the liver, and the most common metastatic pathways are via portal vein and hepatic artery. The symptoms of secondary hepatocellular carcinoma are similar to those of primary hepatocellular carcinoma, but it often develops more slowly than the latter due to the absence of cirrhosis. Secondary liver cancer usually has no characteristic manifestations, and in the early stage, the symptoms are mainly those of the primary foci, and the symptoms of the liver itself are not obvious. As the disease develops and the liver metastases increase in size, the symptoms of the liver are gradually manifested, which can be manifested as discomfort or pain in the upper abdomen, fatigue, emaciation, fever, lack of appetite and lumps in the upper abdomen. Jaundice, abdominal fluid, and malignant disease may appear in the advanced stage of the disease. Physical examination may reveal yellow staining of sclera skin and signs such as hepatomegaly and mobile turbid sounds. If secondary liver cancer is diagnosed, early and standardized treatment is recommended to reduce the adverse effects of the disease.