A hard lump in the right side of the mid-abdomen without pain is feeling uncomfortable, which may be related to colon occupation, neurofibroma, lipoma and other reasons. 1. Intestinal space occupation: such as intestinal polyps, intestinal tumors and other space-occupying lesions, if the volume is large, it can cause a hard lump in the right side of the mid-abdomen, which may not be accompanied by pain, and abdominal distension and other uncomfortable symptoms may occur. 2. Neurofibroma: painless swelling distributed along the nerves under the skin, gradually increasing in size, a few of them may be accompanied by radioactive or burning pain. 3. Lipoma: most of the normal fat-like tissue grows between the subcutaneous and muscle, if it occurs in the right side of the mid-abdomen, it may appear as a raised or palpable mass, most of them are not accompanied by pain, but some patients may feel uncomfortable. It is recommended to find the right side of the mid-abdomen lumps do not hurt, is to feel uncomfortable, go to the hospital in a timely manner to improve the examination, a clear diagnosis and follow the doctor’s instructions for treatment, to avoid delays in the condition.