If you have blisters on your genitals, it is recommended that you go to the hospital for an examination to clarify the cause and then treat it symptomatically. A. If it is a local mechanical or physical irritation that produces a blister of skin tension. If excessive masturbation causes foreskin blisters, it is recommended to disinfect the area with iodophor solution, use a sterile needle, and draw out the herpes fluid. Second, if there is a herpes virus, after the diagnosis is confirmed, it is recommended to give antiviral treatment. You can take oral acyclovir tablets, 400mg/time, 1 time/day, for 1 week, or topical acyclovir ointment, 3 times/day, for 1 week. Third, if there is a local infection, such as prepuce, glansitis, can appear blisters, pustules, it is recommended to apply topical anti-infective drugs. For bacterial infections, it is recommended to apply a little topical Bactrim, 3 times/day for 1 week; for fungal infections, it is recommended to apply a little topical miconazole ointment, 3 times/day for 1 week.