Vulvar fissures, itching may be vulvovaginal pseudomycelium yeast disease, vulvar white lesions, vulvar eczema, contact dermatitis and other diseases, need to be for the cause of the oral Vitamin A drugs, antihistamines, antibiotic drugs, such as fluconazole, Avicenna capsule, loratadine, amoxicillin and so on. 1. Vulvovaginal pseudomycosis: when patients suffer from vulvovaginal pseudomycosis, they may have vulvar fissures, itchiness, accompanied by vaginal slag-like discharge, increased secretion, etc., which can be treated with oral fluconazole and itraconazole. 2. Vulvovaginal leukoplakia: Vulvovaginal fissures and itching may be caused by vulvovaginal leukoplakia. Patients can take oral vitamin A drugs, such as Avicenna capsule, isotretinoin gel and so on. Or you can take oral vitamin drugs, such as vitamin C, vitamin D and so on. 3. Vulvar eczema: Vulvar cracks, itching is also considered to be caused by vulvar eczema. Patients can take oral antihistamines, such as cetirizine, loratadine and so on. Or oral glucocorticoid drugs, such as prednisone, dexamethasone and so on. 4. contact dermatitis: vulvar fissures, itching may also be caused by contact dermatitis. Patients can take oral antibiotics, such as amoxicillin, cefaclor and so on. Can also oral antihistamine drugs, such as cetirizine, loratadine, etc.. Patients taking drugs are required under the guidance of a doctor, do not take medication without authorization, so as not to damage the health of the body.