Principles of early treatment of neonatal hypoxic-ischemic encephalopathy

  The aim of treatment is to improve the metabolic function of damaged neurons as much as possible; to maintain the stability of the internal environment; and to control convulsions and reduce cerebral edema, improve cerebral blood flow and brain cell metabolism and other special treatment.  (a) General treatment: ① Correct hypoxemia and hypercapnia, use artificial respirator if necessary.  (ii) Correct hypotension.  (iii) Supply sufficient glucose to meet the energy metabolic needs of brain tissue.  ④Correct metabolic acidosis.  ⑤Import intravenous calcium gluconate if blood calcium is below 1.9 mmol/L.  (6) Limit fluid intake appropriately (2) Control convulsions.  (c) Control the increase of cranial pressure.  (iv) Central nervous system stimulants, etc.  Cytochrome C triphosphate urea glycoside coenzyme A can be administered intravenously daily until the symptoms improve significantly; cytidine 100-125 mg/day diluted and administered intravenously once a day starting on the second day after birth; brain activator 5 ml diluted with saline and administered intravenously can improve brain tissue metabolism. 14-21 days or longer treatment. Gangliosides are also a good class of neurotrophic drugs.