The treatments for neonatal hypoxic-ischemic encephalopathy include supportive therapy, controlling convulsions, treating cerebral edema, subcooling therapy, other treatments, and rehabilitation training. 1. Supportive therapy: (1) Maintain good ventilation function, keep oxygen partial pressure >60~80mmHg, carbon dioxide partial pressure and pH in normal range. Give oxygen therapy in different ways according to blood gas results. (2) Maintain good cerebral and systemic perfusion: hypotension can be maintained in the normal range with vasoactive drugs such as dopamine and dobutamine to ensure adequate and stable cerebral perfusion. (3) Maintain blood sugar in the normal range. 2. Control of convulsions: Control of convulsions helps to reduce the metabolism of brain cells, and phenobarbital is preferred. 3. Treatment of cerebral edema: diuretic furosemide is preferred when intracranial pressure is increased. 4. Sub-hypothermia treatment: it refers to the artificial induction method to drop body temperature by 2~5℃, in order to reduce energy consumption, reduce extracellular glutamate, oxidative reaction and achieve the role of protection of brain cells, which can reduce the rate of severe disability and mortality. 5. Other treatments: recombinant human erythropoietin, stem cells and other treatments are still in clinical trials. 6. Rehabilitation training: Early rehabilitation training after the condition is stabilized is conducive to promoting the recovery of brain function and reducing sequelae. If the patient is diagnosed with neonatal hypoxic-ischemic encephalopathy, parents should bring him to the hospital in time, and standardize the treatment under the guidance of the doctor in order to reduce the adverse effects of the disease. All of the above medications should be used under the guidance of a doctor, avoid self-medication.