Clinical symptoms of bile duct cancer are related to its site of occurrence, the degree of bile duct obstruction, and the degree of tumor invasion. Generally speaking, cholangiocarcinoma located in the liver, or the peripheral type, has no special symptoms, often only mild symptoms such as abdominal distension, unless most of the liver lobes have been eroded, and jaundice rarely appears, but biochemical tests often reveal abnormalities in special liver function tests such as alkaline phosphate P. If patients with peripheral cholangiocarcinoma have intrahepatic bile duct stones, the frequency of symptoms may vary, for example, they are more likely to have bile duct infections and may have fever and chills. Some patients may be accidentally diagnosed with bile duct cancer after undergoing surgery for acute cholangitis. If the cholangiocarcinoma grows in the hilar part of the liver, so-called hilar cholangiocarcinoma, and cholangiocarcinoma of the extrahepatic bile ducts, the common symptoms include abdominal pain, because it can easily cause bile duct obstruction, jaundice and itchy skin. It is estimated that more than 80% of this type of bile duct cancer will present with jaundice, and the stool will become lighter or even white in color. In addition to biochemical abnormalities, liver cells may also be affected by prolonged bile duct obstruction, and blood clotting may be prolonged over time. Bile duct cancer usually does not grow quickly, but if there is pain, it often indicates that it is quite serious and has spread to the terminal stage. This is also the reason why early diagnosis of bile duct cancer is not easy. Also, if bile duct cancer occurs in the upper part of the bile duct, the symptoms are milder and more obscure. Although jaundice and other symptoms appear earlier in the hilar and extrahepatic bile duct types, this does not mean that the prognosis is better.