Surgery is the preferred method for the eradication of encapsulation and should be performed before the onset of compression symptoms or complications. There are two main types of surgery: internal capsulotomy and external capsulotomy. In internal capsulotomy, the fluid is first removed with a fine needle (to prevent spillage of the fluid), and then the internal capsule is removed. The internal capsule is only mildly adherent to the external capsule, so it is easy to peel off and can often be removed completely. The lung, brain, bone and other parts of the encystment should also be removed. Before surgical removal of the internal capsule, hypertonic saline is injected into the capsule to help kill the protozoa. Depending on the location and size of the lesion, external capsulotomy may be used as appropriate. Benzimidazoles are antihelminthic drugs that have been studied at home and abroad in recent years, and have been used clinically on the basis of animal experiments and have achieved certain efficacy. According to the WHO opinion, both albendazole and mebendazole are listed as the first choice of antihelminthic drugs. Some authors believe that their indications are as follows: ① Secondary abdominal or thoracic cavity encysted worm disease, which mostly occurs after the rupture of primary liver or lung cystic encysted worm disease, or due to poor protection during the operation of encysted worm, or due to the misuse of diagnostic puncture, resulting in the overflow of encysted fluid, secondary to the spread of implantation, lesions throughout the abdominal or thoracic cavity, which is difficult to eradicate surgically. ② Multiple or multi-organ cystic encysticercosis, or recurrent encysticercosis, the patient is unwilling or difficult to accept re(multiple) surgery. ③The patient is old and frail or has coexisting organic diseases of important organs and poor surgical tolerance. ④In advanced hepatic vesicular coccidioidomycosis that is surgically explored or not curable, or secondary to pulmonary or cerebral metastases, drug treatment can relieve symptoms and prolong survival. ⑤ Regardless of cystic or vesicular coccidioidomycosis, chemotherapy as an adjuvant before and after surgery can reduce the recurrence rate and improve the efficacy. After the introduction of cobendazole, there is a trend to replace mebendazole in the treatment of encapsulated worm disease. Albendazole is better absorbed and its serum concentration is 100 times higher than that of mebendazole. The concentration in the cyst fluid is 60 times higher than that of mebendazole. In the treatment of cystic encysticercosis, the dose is 10-40mg/kg per day, divided into 2 doses, 30 days as a course of treatment, depending on the condition of several consecutive courses, the course of treatment is better than mebendazole, especially for pulmonary encysticercosis. For vesicular encystment, some people in China suggest long-term treatment with higher dose of albendazole, the daily dose is 20mg/kg, the course of treatment can be from 17 months to 66 months (the average is 36 months), after long-term follow-up, it is found that the CT scan shows obvious progress, most of the cases are cured by calcification of the original lesion area, the efficiency rate is 91.7%. The patients generally tolerated the long-term treatment and no serious toxic side effects were observed, but follow-up of liver and kidney function and bone marrow is recommended during the treatment. It is contraindicated in pregnant women. Mebendazole is used in different doses and treatment courses abroad. The dose varies from 20 to 200 mg/kg per day, usually 40 to 50 mg/kg per day, divided into three oral doses for one month, followed by a half-month break and another course of treatment, usually for three months. It is also believed that the treatment of cystic encysticercosis requires 1-6 months of medication, while the treatment of vesicular encysticercosis requires an extended course of treatment, up to 3-5 years for a long time. Some patients with cysticercosis can be expected to be cured, and pulmonary coccidiosis is more effective than hepatic coccidiosis. Mebendazole is poorly absorbed, generally only 1% is absorbed on an empty stomach, in order to improve the efficacy, the drug should be taken with a fatty meal, the drug can be easily absorbed with fat.