At present, there is no effective treatment for advanced gastric cancer, and the death rate is relatively high, and the 5-year survival rate after active treatment is still less than 30%. Advanced gastric cancer generally refers to stage IV gastric cancer, at this time, the tumor has invaded the plasma membrane or adjacent tissues and structures, usually accompanied by lymph node metastasis and distant metastasis, which is often incurable and will lead to death. Therefore, the main therapeutic goal in this period is to improve the quality of life and prolong the survival period of patients. Chemotherapy, radiotherapy, targeted therapy and other comprehensive treatments are often given in clinics. Since the survival rate of advanced gastric cancer is low, it is recommended to have annual physical examination to screen for cancer, and once gastric cancer is diagnosed, early treatment should be carried out to improve the prognosis and prolong the survival period.