In patients with brainstem infarction, if the infarct is large, death may occur in 3-5 days in the acute phase because of cerebral edema. In contrast, if the brainstem infarct is small or is treated aggressively, there is generally no effect on the patient’s life expectancy. Patients with brainstem infarction will have symptoms such as sensory impairment of the contralateral limb, activity impairment, limb hemiparesis or dizziness, choking and coughing. After timely treatment with anticoagulation, fibrin-lowering, thrombolysis or antiplatelet and cerebral protection, the patient’s brain tissue will be saved and the symptoms of infarction and limb hemiparesis will gradually improve with the progress of the disease. If sequelae are left, they can be recovered through systematic rehabilitation training in the rehabilitation department. In this case, secondary prevention of cerebrovascular disease should be initiated to prevent cerebral infarction, which does not have much impact on the life expectancy of patients.