Elderly people who urinate frequently at night may be caused by physiologic factors, prostate enlargement, overactive bladder syndrome, diabetes mellitus, with different triggers and different solutions, including medication and surgery. 1. Physiological factors: for example, excessive drinking or psychogenic urinary frequency, generally do not need special treatment, should control the amount of water consumption, and improve the psychological state, usually can be relieved by themselves. 2. Prostatic hyperplasia: For nocturia caused by prostatic hyperplasia, it can be treated with drugs such as tamsulosin and finasteride. When the lesion is serious or the drugs are ineffective, surgical treatment can be considered, for example, transurethral resection of the prostate. 3. Overactive bladder syndrome: Overactive bladder syndrome can also lead to frequent urination at night. After diagnosis, bladder stabilizing drugs can be used to regulate the bladder, such as Tolterodine tablets and Solynacin tablets. 4. Diabetes mellitus: For frequent urination at night caused by diabetes mellitus, long-term treatment with oral hypoglycemic drugs, such as metformin, and insulin injection should also be considered in serious cases. During the treatment period, patients should not use drugs arbitrarily, should follow the doctor’s instructions, safe and reasonable application of drugs, to avoid improper use of drugs caused by serious adverse reactions.