Fever of 38.5 degrees after hepatic microwave ablation may be caused by normal postoperative reaction, infection, blood transfusion, etc. Normal postoperative reaction can be treated with physical cooling and symptomatic treatment; infection can be treated with penicillin, cephalosporin and other antibiotic drugs, and fever caused by blood transfusion can be caused by intramuscular injection of dexamethasone. 1. Normal postoperative reaction: hepatic microwave ablation is to make liver tumor tissue necrosis with thermal injury, and the necrotic tissue is absorbed by the body after the operation, and there is absorbed heat and the body temperature rises to 38.5 degrees. At this time, patients should be closely observed, and physical cooling and symptomatic treatment should be carried out through warm water bath, ice pack or alcohol bath. 2. Infection: Incomplete sterilization or violation of aseptic operation during surgery can cause wound infection and postoperative fever. At this time, you can use penicillin, cefoperazone, cefuroxime and other antibacterial drugs to fight infection. 3. Blood transfusion: (1) If blood of incompatible blood type or blood products themselves are contaminated during surgery, etc., it can lead to postoperative fever in patients. If hemolytic reaction is caused by blood group incompatibility, inotropic glucocorticoid can be used to weaken the immune response of the body, and auxiliary use of antipyretic and analgesic drugs (e.g., acetaminophen tablets) can be used to lower the body temperature; (2) Antibacterial drugs such as cephalosporin and macrolides (e.g. cefoperazone, azithromycin, etc.) can be used for fever caused by contamination of blood products. Therefore, there are many reasons for fever of 38.5 degrees after hepatic microwave ablation, patients should go to the hospital in time, give targeted treatment after clarifying the cause of the disease, and follow the doctor’s instructions for medication.