A five-year-old boy always wetting the bed is considered to be due to enuresis, and should take general treatment, medication, other treatments and other ways to improve. 1. General treatment: For five-year-old boys who always wet the bed, parents first need to help them recognize the cause of enuresis, avoid blaming the child, help the child to establish confidence, reduce the child’s psychological burden. At the same time, we should regulate the child’s work and rest and meals, drink more water during the day, and limit the intake of water and food about 3 hours before bedtime. Educate the child to develop the habit of regular urination, to empty the bladder before bedtime. 2. Medication: Urinary loss can also be treated with medication. Desmopressin is the first line of treatment for enuresis and needs to be taken 1 hour before bedtime. For children with overactivity of the urethral muscles, anticholinergic drugs such as oxybutynin can be taken as prescribed by the doctor. 3. Other treatments: For children with poor drug efficacy, biofeedback therapy can be taken, through repeated training, the child can learn to contract and relax the pelvic floor muscles. For children with overactive bladder, transcutaneous electrical nerve stimulation can be considered. Parents are advised to take their children to the hospital for diagnosis and treatment.