There is no such thing as which medicine is better, Abiraterone or Bicalutamide. Abiraterone and bicalutamide are the main drugs used in the treatment of prostate cancer, patients need to choose according to the condition under the guidance of the doctor. The main component of abiraterone is abiraterone acetate, which is mainly used to treat metastatic desmoplasia-resistant prostate cancer, and can inhibit androgen synthesis to achieve the purpose of slowing down the development and spread of prostate cancer. Some patients may have diarrhea, upper respiratory tract infection, liver function impairment and so on. Bicalutamide tablets, the main ingredient of which is bicalutamide, belongs to non-steroidal androgen receptor inhibitor, inhibits androgen stimulation, leading to the shrinkage of prostate tumors, and can be used for patients with locally advanced prostate cancer without distant metastasis. Some patients may experience adverse reactions such as vomiting, fatigue or dizziness after taking the drug. Patients should choose and take the drug under the guidance of professional doctors, not blindly self-medication, and need regular review during the medication. If any discomfort occurs during the medication, patients should go to regular hospitals for consultation.