Listen to me slowly …… 1, our arterial blood vessels are divided into three layers: the inner membrane, the middle layer, and the outer membrane (the following figure). 2.We have cholesterol in our blood. 3.If cholesterol enters under the intima and gradually accumulates, it forms atheromatous plaque (the following picture). 4.After plaque is formed in arteries, the lumen of blood vessels will become narrower and narrower, causing ischemia in corresponding parts of tissues and organs (such as heart, brain, etc.). This is the pathogenesis of coronary heart disease and cerebral infarction (figure below). 5. The lining of blood vessels in healthy people is very tight, and it is difficult for cholesterol to enter. So, why would someone develop atherosclerotic plaque? 6.Well, let’s say: if atherosclerotic plaque is a bowl of porridge, cholesterol is the rice used to make porridge. You can’t make porridge with only rice and no fire. Where is the fire? High blood pressure, diabetes, smoking is the fire!