Tooth pain is usually caused by anaerobic bacteria infection caused by pulpitis, apical periodontitis, periodontitis, etc., clinically need to carry out root canal treatment or periodontal treatment, some patients need to use drugs to reduce inflammation, commonly used nitroimidazole drugs to treat local infections caused by anaerobic bacteria, including metronidazole, tinidazole and so on. 1. Metronidazole is mainly composed of 2-methyl-5-nitroimidazole-1-ethanol, which has a strong killing effect on anaerobic bacteria. Tinidazole: the main component is 2-methyl-1-[2-(ethylsulfonyl)ethyl]-5-nitro-1H-imidazole, used for the treatment of various infections caused by anaerobic bacteria. Compared with metronidazole, tinidazole has a high blood concentration after oral administration and a long duration of effective concentration. 2. It should be noted that the use of drugs can only temporarily relieve the symptoms, and the drug is almost ineffective for pulpitis, pulpitis and apical periodontitis need to be thoroughly root canal treatment to cure. Periodontal disease requires removal of localized tartar and plaque, and periodontal treatment through scaling and scraping. All of the above medications should be used under the guidance of a doctor, and it is recommended that you visit a hospital to receive regular professional treatment.