Can intrahepatic bile duct stones heal on their own?

No. Once formed, stones are difficult to heal on their own, and intrahepatic bile duct stones can easily enter the common bile duct and become secondary extrahepatic bile duct stones. Intrahepatic bile duct stones can be complicated by serious complications such as biliary cirrhosis and bile duct cancer in the distant future, and intrahepatic bile duct stones are still a common and difficult to treat biliary tract disease in China.