Although flumethasone and mometasone furoate are both glucocorticosteroids, they have different indications, effects, and adverse reactions, so there is no such thing as which one is more effective. Flumethasone is suitable for seborrheic dermatitis, psoriasis, contact dermatitis, palmoplantar hyperkeratosis, etc., with anti-inflammatory, anti-tissue proliferation, vasoconstrictive effect. Mometasone furoate is indicated for neurodermatitis, eczema, and pruritus with anti-inflammatory, antipruritic, ooze-reducing, and anti-allergic effects. Patients should be under the guidance of the doctor, according to different diseases to choose the appropriate drug treatment, so there is no which efficacy is better. Some patients may experience adverse reactions such as skin pigmentation, irritation, dryness, and capillary dilation after topical use of mometasone furoate. Adverse reactions such as itching, tingling, perioral dermatitis, and burning sensation may occur after topical mometasone furoate. It is important to note that it is contraindicated in patients presenting with viral infections of the skin and in flumethasone-allergic patients; it is contraindicated in patients allergic to mometasone furoate. If you want to use topical flumethasone or mometasone furoate, it is recommended to go to a regular hospital to consult a doctor and use the medication under the doctor’s guidance, and not to use the drug without authorization.