Uremic poisoning is uremia, which has a variety of clinical manifestations because of the damage to multiple body systems in all stages of uremia. In the early stage, loss of appetite is the first symptom, often accompanied by nausea and vomiting. Due to the loss of appetite, symptoms of anemia gradually appear, such as dizziness, weakness, and pallor, and because excess water and sodium cannot be excreted in time, patients develop hypertension and are more persistent. Patients almost always have symptoms of edema, varying in severity from oedema of the eyelids or both lower limbs at the beginning to generalized edema at a later stage. As hypertension mainly damages the heart and blood vessels, patients may suffer from panic attacks and chest tightness, while others may suffer from arrhythmias.