Plasma cell mastitis is a chronic, non-bacterial inflammation of the breast; it can be cured by a total mastectomy given to a patient with plasma cell mastitis, which removes the lesion in its entirety. Total mastectomy can remove the diseased ducts, lumpy tissue and fistulae, so it can be cured. However, the need for total mastectomy depends on the condition of the disease, and total mastectomy is not always necessary. For the formation of breast abscess, abscess incision and drainage can be given; the lesion has formed a lump, but more limited, can be removed when the lump tissue; because of the recurrence of fistula formation, the need for complete removal of fistula. For the formation of fistulas more, a larger scope, or even throughout the breast, or the formation of a large swelling, occupying half or the entire breast, can be given to the simple mastectomy, after the operation can basically be completely cured. The specific situation is recommended to go to the hospital, complete the examination, the professional physician for the patient’s condition to give appropriate treatment.