Stage III of membranous nephropathy is mainly characterized by massive proteinuria, severe hypoproteinemia, hyperlipidemia and edema. There is usually no inevitable connection between the pathology of membranous nephropathy and the clinical manifestations of patients. Patients with membranous nephropathy stages I-IV have similar clinical manifestations, mainly nephrotic syndrome, i.e., large amount of proteinuria, severe hypoproteinemia, hyperlipidemia and edema, etc. Most of the clinical symptoms of patients with membranous nephropathy are manifested as nephrotic syndrome. Most of the clinical symptoms of patients with membranous nephropathy are nephrotic syndrome, and some of them are accompanied by microscopic hematuria, and renal function impairment may occur with the progression of the disease. The disease is prone to thromboembolic complications. Patients with stage III membranous nephropathy are advised to go to regular hospitals in time and receive standardized treatment under the guidance of doctors.