Autologous fat filling for face includes periorbital, temporal, forehead, apple muscle, cheeks, chin, root of nose and other parts, which is widely used, mainly to purify and process the self-fat that is sucked out of the body, and then injected into the face accurately, which can be used to fill the facial depressions and contouring. Autologous fat filling injection requires multi-point, multi-layer, and strict control of the injection volume. If you choose an irregular and unprofessional organization to perform the surgery, the following side effects may occur: 1) the area where the fat is extracted and the area where the fat is filled may be uneven; 2) the survival rate of the fat in the filled area is too low, which does not meet the ideal expectation; 3) improper operation or inexperience of the operator may lead to the destruction of subcutaneous blood vessels and the formation of fat embolism; 4) the fat embolism may result in the formation of fat embolism. If the operator has poor sense of asepsis or operates for too long, it may lead to infection of the liposuction or filling site; 5. If too much fat is filled at one time, hard nodules and calcification may occur. To summarize, when patients want to undergo autologous fat filling of the face, they should go to regular hospitals to seek professional doctor’s help. After autologous fat grafting facial filling, the first 3 days can be appropriate cold compress, cold compress time to about 30 minutes each time is appropriate, 3 days later can be hot compress, accelerate the disappearance of edema; due to the use of injection, postoperative needle eye 7 days is recommended to avoid water, to prevent wound infection; in 3 months to avoid making a large expression as well as filler parts of the massage.