Superficial, hard subcutaneous nodules in the upper outer quadrant of the female breast that resemble elephant skin should be considered as a possible filarial nodule. How to prevent superficial hard subcutaneous nodules like elephant skin in female breast? 1, census and treatment Early detection of patients and people with worms, timely cure, both to ensure the health of the people, but also to reduce and eliminate the source of infection. Census should be 1 year old and above all residents as the target, requiring more than 95% of residents to receive blood collection. 2, mosquito prevention and control. Cut off the path of transmission, eliminate mosquito breeding sites. In the mosquito season, it is best to use mosquito nets; outdoor work, pay attention to be coated with anti-mosquito oil, mosquito repellent and other repellents in exposed parts of the skin, the head available cotton thread impregnated with 701 anti-mosquito oil made of anti-mosquito nets. 3, strengthen the epidemiological surveillance of the area has reached the basic elimination of filariasis indicators. In the monitoring work should pay attention to: ① to the original positive patients to review and treatment, the previous unchecked to make up for the treatment, while strengthening the management of mobile populations, found patients, timely treatment until the negative. ② strengthen the blood test positive mosquito vector monitoring, found infected mosquitoes, that is, the infected mosquito household as the center, to the surrounding population to expand blood checks and mosquito control, in order to clear the epidemic site to prevent continued transmission. Filariasis in the south of China is one of the four major parasitic diseases, transmitted by mosquito bites, and patients living together normally does not lead to infection with the disease. In the filariasis endemic area census and universal treatment of patients and people with microfilariae, to improve the prevention of mosquitoes, mosquito control work, the prevention of filariasis is important.