The role of Chinese medicine in the prevention and treatment of cerebral hemorrhage

       Cerebral hemorrhage is a non-traumatic hemorrhage in the brain parenchyma. Cerebral edema is an important complication of cerebral hemorrhage, and its development is an important cause of neurological deterioration and even death. Experimental studies on cerebral hemorrhage show that cerebral edema is a mixture of vascular and cytotoxic cerebral edema.  A large number of experimental studies have shown that Chinese medicine has good preventive and curative effects on cerebral edema after cerebral hemorrhage: 1) protection of blood-brain barrier 2) anti-free radical damage 3) anti-neurotoxic effects Evaluation and prospect: cerebral edema after cerebral hemorrhage can increase intracranial pressure, causing brain herniation and brainstem compression, leading to death. At present, modern medical treatment methods mainly use dehydrating agents, diuretics and glucocorticoids, which not only have obvious side effects, but also are poorly targeted to the pathophysiological mechanism.  Chinese medicine has a long history of prevention and treatment of cerebral hemorrhage, and its efficacy is precise, its pathways of action are multifaceted, and there are no obvious toxic side effects, and it can regulate the overall condition of patients, which has a comprehensive therapeutic efficacy that cannot be replaced by Western medicine. The mechanism is multi-linked and multi-targeted, which can reduce vascular-derived and cytotoxic brain edema after cerebral hemorrhage in terms of protecting the blood-brain barrier, anti-free radical damage and anti-neurotoxic effects.  However, in modern pharmacological studies on the mechanism of anti-brain edema after cerebral hemorrhage in Chinese medicine, positive control chemical drugs are generally not selected, so it is difficult to draw more definite conclusions. At present, the research methods are still backward, and CT and MRI are not used in pharmacodynamic studies to quantify the size of cerebral hematoma and the extent of cerebral edema; local cerebral blood flow measurement is also rarely used. At the same time, Chinese herbal compound preparations are characterized by complex components, multifaceted effects, and easy interference. Therefore, to clarify the specific mechanism of its anti-brain edema after cerebral hemorrhage, it is necessary to explore biochemically, pharmacologically, and molecular biologically, to actively search for effective Chinese herbal prescriptions, to further compare the efficacy of each treatment method in treating cerebral hemorrhage, and to thoroughly study its mechanism of action.