The use of half-summer with epiphyllum is a contraindication, which will lead to increased toxicity of epiphyllum, accelerated absorption, and will also reduce the efficacy of half-summer and epiphyllum. Half-summer and epiphyllum together belong to the eighteen contraindications in the Chinese medicine compounding taboo, “Ru Men Qi Zi Zi” records, half piper Bei Zhen Bian Bian attack Wu, refers to half-summer and epiphyllum can not be used with the epiphyllum together. Half-summer and epiphyllum will lead to a significant increase in the content of bi-ester type aconite alkaloids with strong toxicity and faster absorption. It will also reduce or delay the anti-inflammatory and analgesic effect of Chuanwu, and interfere with the cough suppressant effect of hemixia. Half-summer should be used with caution in cases of yin deficiency and dry cough, dry phlegm, hot phlegm, and blood. Half-summer should not be used with epiphyllum, Chuanwu, and Caowu, and the raw product should be taken with caution. Pregnant women and people with yin deficiency and hyperactivity should not use epiphyllum, and epiphyllum should not be used with half-summers, gua-pao, bai zhi, bei mou, bai he. It is recommended to go to the hospital in time when you feel unwell, and the use of Radix et Rhizoma Pinelliae and Radix et Rhizoma Pinelliae should be guided by a professional doctor, please don’t use them by yourself.