Lung nodules have been present for 40 years, and need to be combined with clinical symptoms and regular follow-up with imaging to determine whether they are serious or not, and cannot be generalized. 1. Lung nodules for 40 years without any discomfort. It means that the lung nodules may be caused by chronic inflammation. If there is no change in the size and nature of the lung CT on regular follow-up, there is no need to do special treatment. However, you should avoid smoking and drinking and overwork, and eat a light diet. 2. If you feel uncomfortable symptoms such as chest pain, cough, sputum, shortness of breath, chest tightness, fatigue, etc., or if changes in nodules can be seen in chest CT, there is a possibility that the lung nodules may have malignant changes, which is more serious. It is recommended to go to the hospital as soon as possible to further clarify the nature of the nodule, and follow the doctor’s instructions for treatment.