Fibroadenoma and breast cancer have different mechanisms of occurrence. Fibroadenoma does not malign to breast cancer, even if it is bigger. However, fibroadenoma can malign into lobular tumor, which used to be called lobular cystic sarcoma. More than half of the patients with lobular tumor are not undergoing surgery for the first time, and the first few surgeries are for fibroadenoma, and then they keep recurring after surgery, with shorter and shorter intervals each time, and the tumor growth becomes more and more active, gradually going to low malignancy, moderate malignancy or even high malignancy. The specific mechanism is not very clear, but the high concentration of inflammatory factors in the incision area after surgery certainly contributes to the recurrence. I have met several patients with post-operative fibroadenoma wound infection, and the recurrence occurred within three months after surgery, which is basically impossible in ordinary fibroadenoma patients. Fibroadenoma is rarely solitary, and it is not common to find patients who will never have a recurrence after cutting it out for life. So I think: if you have a small single or multiple fibroadenoma, you don’t need to pay any attention to it at all, unless there are three cases that require surgery: 1. the mass is suspected to be malignant under ultrasound or mammogram 2. the mass gradually increases in size and affects your life 3. there is a situation where the mass suddenly becomes larger There is a situation that requires consideration of surgery, but it is not necessary: you will be pregnant, which may stimulate the mass to become larger. Of course, if you just want to have surgery and have itchy hands, it is not against the principle that you can cut at any time. Our desire is simply to not cut if we can – the wound is a permanent memento that the surgeon leaves for the patient. Fibroadenoma is a fibrous epithelial tumor, the lesion site can be divided into five types, 1, intraductal type: the lesion site is the subepithelial connective tissue of the glandular duct 2, periductal type: the lesion site is the peri-epithelial connective tissue around the glandular duct 3, mixed type: both 4, cystic hyperplasia type: the lesion site is the epithelial and subepithelial or extra-elastic connective tissue of the glandular duct 5, giant type: the onset site is not special. In contrast, breast cancer is a lesion that originates from the terminal lobular unit. The site of onset is different. Fibroadenoma can be combined with breast cancer. Some hospitals have counted 10,316 cases of fibroadenoma, among which 4 cases were combined with breast cancer, the incidence rate is 0.038%, which is similar to the incidence rate of 34/100,000 of breast cancer in general. This is similar to the incidence of breast cancer in the general population of 34 per 100,000. It should not be assumed that fibroadenomas can become malignant to breast cancer. Fibroadenomas can undergo sarcomatous transformation and are actually malignant, not lobulated tumors. — This statement is very confusing as to what he means. Let’s see what kind of sarcoma can actually grow in the breast. Lobular cystic sarcomas often occur on the basis of the intraductal type and develop in women over the age of 45, many with a history of multiple surgeries for fibroids. Carcinosarcomas, on the other hand, originate from multipotent differentiated stem cells with bidirectional differentiation. It does not originate from fibroadenoma. Mesenchymal sarcoma, consisting of a pure mesenchymal component without epithelial component, originates from a specific mesenchymal component within the lobules of the breast that is responsive to hormones. 2003WHO microscopic features consist of open ducts and cuffed enclosing ducts of spindle-shaped cells. There are no findings that he is related to fibroids. The others: angioendothelial sarcoma, malignant fibrous group, liposarcoma, lymphoma and fibroma are even more distantly related.