The key points of postoperative care for colon esd (endoscopic mucosal dissection) include close monitoring, reasonable diet, and maintaining a healthy living condition. 1. Close monitoring: although the trauma of colon esd is relatively small, bleeding, perforation and infection complications may occur, therefore, it is necessary to closely monitor the basic vital signs such as blood pressure, respiration, heart rate, etc., and deal with the symptoms such as abdominal pain, vomiting of blood and black stools in time after the operation. 2. Reasonable diet: generally fast for 2-3 days after surgery to avoid food residue stimulation of trauma, and gradually give fluids and semi-fluids with the recovery of intestinal function. In order to ensure energy supply, parenteral nutritional support is needed. Pay attention to the strict cessation of smoking and alcohol, avoid drinking strong tea, strong coffee and other stimulating beverages. 3. Maintain a healthy living condition: After surgery, you need to take reasonable rest, avoid staying up late, avoid emotional excitement and excessive pressure. When discomfort occurs after colon esd surgery, it is recommended to call the healthcare personnel in time to avoid delaying the condition.