The causes of upset stomach and foreign body sensation in the throat include dietary factors, mental factors, and gastroesophageal reflux disease (GERD). The selected treatments are different depending on the cause of the disease. Commonly used treatments include dietary adjustments, psychological guidance, medication such as omeprazole, mosapride, aluminum thioglycollate and so on. 1. Dietary factors: due to eating cold and spicy food, it stimulates the esophagus, pharynx and gastric mucosa, leading to mucosal damage and triggering symptoms such as gastric discomfort and foreign body sensation in the throat. Patients can adjust their diet to light and easy to digest food, avoid spicy and stimulating food, reduce the burden on the stomach, so as to alleviate the symptoms. 2. Mental factors: due to anxiety, nervousness, depression and other mental factors, triggering the patient’s sympathetic nerves over-excitement, resulting in stomach discomfort, foreign body sensation in the throat phenomenon. The patient’s mood can be improved through psychological counseling, such as finding others to talk to, traveling, etc., so as to alleviate the discomfort symptoms. 3. Gastroesophageal Reflux Disease (GERD): If the lower esophageal sphincter is relaxed, it is easy to cause gastric contents in the stomach to reflux into the esophagus, pharynx, mouth and other parts of the body, which can stimulate the mucous membrane of the pharynx to be damaged, resulting in gastric discomfort and a foreign body sensation in the patient’s throat. You can choose medication, such as omeprazole, mosapride, thioglycollate oral solution, etc., to inhibit the secretion of gastric acid, promote gastrointestinal dynamics, and protect the gastric mucosa, so as to improve the symptoms. If the symptoms of stomach discomfort and foreign body sensation in the throat occur frequently, it is recommended that patients go to the hospital in time. Improve gastroenteroscopy, color ultrasound and other examinations, and follow the doctor’s instructions for treatment.