In life, we often hear this sentence in the nagging of elders that we must be safe and sound when we go out. However, in real life, some people may suffer from cranial defects due to some irresistible natural or man-made disasters. In neurosurgical guidelines, when the defect area reaches 3*3cm or more, cranial repair is required 2-3 months after debridement and decompression. What is the full cost of repair surgery for a 12*12 cm cranial defect? In cranial bone repair surgery, patients are widely concerned about the cost of the surgery and the safety of the surgery, for the cost of the surgery, different patients, the area of the defect is not the same, to take the treatment plan is also different, so the specific cost can not be generalized. As a routine surgery in neurosurgery, cranial bone repair is a very mature technology, and the surgery is very safe, basically there is no danger. Of course, when doing cranial repair surgery, the choice of repair method and implant material is also very important, because the appropriate repair method and excellent implant material can achieve a better repair effect, but also conducive to the patient’s postoperative recovery. At present, peek cranioplasty has achieved remarkable clinical results since its clinical use. This surgery is an early reference to Europe and the United States advanced plastic surgery concepts, hundreds of cases of successful clinical experience to summarize, and constantly improve and upgrade the technology. At present, it has 4 technical innovations, and has made personalized adjustments in the thickness of the material and the mesh, which is conducive to increasing blood flow and effectively preventing temporal muscle atrophy. At the same time, the innovative introduction of cosmetic concepts, such as subcutaneous free, skin flap transfer, myotendinous flap with tibial transfer, eyebrow arch, etc., the postoperative appearance of symmetry, the overall natural and beautiful.