Progesterone may take effect in about 2-3 days or within a week, the time needs to be judged according to the purpose of the medication, the dose of medication, personal reaction to the drug, etc., as follows: 1, if used to promote menstruation, generally within a week after stopping the medication; 2, if used to protect the fetus, bleeding may slowly stop in about 2-3 days of medication, if the embryo continues to grow and develop, dynamic observation or adjustment of medication is required. Progesterone injection is an oily preparation, more difficult to be absorbed by the body, local hard knots can appear, should pay attention to change the injection site. And women can do appropriate hot compresses, or paste fresh potato slices to promote the absorption of hard nodes, dissipation. Women should strengthen their diet and nutrition, eat more fresh vegetables and fruits to replenish vitamins, arrange their work and rest time reasonably, and avoid overworking.