Nail extraction is the fastest and most effective way to treat gray nails, then apply topical antifungal medication, such as Luliconazole cream, bifonazole gel, miconazole cream, ketoconazole cream for 4-6 weeks, and follow up after observing the efficacy. At the same time, oral antifungal medication must be taken, such as terbinafine tablets 2 tablets once a day for 1 month, or itraconazole capsules 200 mg per day for 1 month, once a day. Terbinafine tablets and Itraconazole may have some effect on liver and kidney function, so regular liver and kidney function tests should be done, and if there is any change in liver and kidney function, the drug should be stopped immediately. Do not get the wound area wet after nail extraction, pay attention to the personal protection of the feet, clean the location that is not the nail every day, 1 day cleaning, after cleaning, quickly blow dry the feet, shoes, insoles, socks should be often exposed to the sun, wash often to prevent fungal infection, and also Chinese herbal medicine treatment.