Clinical presentation Like any mediastinal tumor, the clinical symptoms of thymoma arise from compression of surrounding organs and from the symptoms specific to the tumor itself – the comorbidity syndrome. Small thymomas mostly have no clinical complaints and are not easily detected. When the tumor grows to a certain size, the common symptoms are chest pain, chest tightness, cough and anterior chest discomfort. The nature of chest pain is not characteristic, the degree is different and the location is not specific, generally speaking, it is mild and often treated symptomatically without further examination. If the symptoms persist for a long time, some patients may undergo X-ray examination, or some patients may find mediastinal mass shadows during chest X-ray or chest radiography. The overlooked thymoma often grows to a large size at this time, compressing the veins or showing signs of superior vena cava obstruction syndrome. Severe chest pain, rapid worsening of symptoms within a short period of time, severe irritating cough, dyspnea due to pleural effusion, shortness of breath due to pericardial effusion, and skeletal pain of peripheral concern all suggest the possibility of malignant thymoma or thymic carcinoma. The unique manifestation of thymoma is the combination of certain syndromes, such as myasthenia gravis (MG), pure red blood cell aplastic anemia (PRCA), hypoglobulinemia, nephritis nephrotic syndrome, rheumatoid arthritis, dermatomyositis, lupus erythematosus, and megalophagia. Diagnosis Chest CT is an advanced and sensitive method to examine mediastinal tumor. It can accurately show the location, size, protrusion to one side or both sides, the edge of tumor, the presence of surrounding infiltration and the determination of surgical resectability, and it has special value for cases that cannot be diagnosed by clinical and ordinary X-ray examination. Treatment Mediastinal tumors can be treated by conventional median splitting or by televised thoracoscopic techniques. The surgical incision is three incisions of about 1-1.5 cm on the right chest wall, which is characterized by small surgical incisions, fast postoperative recovery and beautiful incisions.