Botulinum toxin mainly acts on nerve endings to inhibit the release of acetylcholine, so as to inhibit nerve impulse conduction and paralyze the muscles. After the injection into the calf, the calf muscle does not feel the nerve impulse conduction, gradually causing the muscle to produce a certain degree of atrophy, so as to achieve the purpose of calf thinning. The specific method of surgery is to draw some grid lines on the calf and determine the specific number of points to be injected according to the degree of calf muscle hypertrophy. After drawing the grid, according to the injected points, mainly the gastrocnemius muscle, inject the prepared diluted botulinum toxin, each point in 3 units, each point is about 2 cm apart, usually according to the calf hypertrophy, the left and right respectively not more than 150 units. But if the operation is not appropriate, after the injection of botulinum toxin leg thinning will also have the following serious consequences: 1, because botulinum toxin is an immunogenic protein, injected into the body is easy to form antibodies in the blood, the injection of excessive amounts will induce the phenomenon of immune overload, damage to the human immune system, triggering vascular abnormalities, inducing immune diseases. In serious cases, there may even be allergies, shock and other adverse reactions; 2. The common sequelae of improper botulinum toxin injection, such as muscle paralysis, affecting mobility, and in serious cases, muscle atrophy can be induced; 3.