A lump found in the male breast that is painful to squeeze is most often considered to be due to gynecomastia or inflammation of the mammary glands. In addition, very few patients consider breast tumors, and male breast cancer accounts for 1% of female breast cancer. Therefore, men who find breast lumps should also promptly visit the breast surgery department of the hospital to have breast ultrasound, axillary lymph node ultrasound, routine blood tests, and if necessary, blood sedimentation, calcitoninogen, and C-reactive protein tests to facilitate the exclusion of inflammatory lumps. Ultrasound examination allows assessment of the mass for changes in size, number, borders, hematologic condition, aspect ratio, texture, lymph node cortex, lymph node medulla, lymph gland, and other structures. If the mass is considered to be inflammatory, it is recommended to give anti-inflammatory treatment and topical application of Ruyi Jinhuang San can be applied topically. If the mass is considered to be malignant or highly suspicious of malignancy, it is recommended that the mass be removed promptly and a rapid pathological examination be performed to clarify the diagnosis. If the lump is considered to be a breast gland hyperplasia and the conservative treatment is not effective, surgery can also be considered to remove the hyperplastic gland.