Lumbosacral pain is mainly caused by lumbar disc herniation, gynecological inflammation, etc. It can be treated by physical therapy, oral medication such as moxifloxacin and surgery. 1. Lumbosacral muscle strain: sedentary, improper posture can cause lumbosacral muscle strain, with long-term chronic pain in lumbosacral area as the main clinical manifestation, mostly aggravated after exertion, generally correct the sitting posture, can be relieved after rest, if the rest can not be relieved, can be relieved by hot compresses, physiotherapy to alleviate the symptoms. 2. Lumbar disc herniation: with lumbar pain as the main symptom, mostly accompanied by radiating pain in the buttocks and lower limbs, the main ways of relieving it are bed rest, oral neurotrophic drugs such as compound methylcobalamin tablets to relieve. It can cause allergy, loss of appetite, nausea, vomiting and other adverse reactions, and is contraindicated in patients with a history of allergy to methylcobalamin or any of the excipients in the prescription. Surgery is required for severe cases. 3. Gynecological inflammation: mainly including adnexitis, pelvic inflammatory disease, pelvic effusion, etc., with lumbosacral discomfort as the main symptom, oral anti-inflammatory drugs moxifloxacin can be used to improve the symptoms. Adverse effects include peripheral neuropathy, tendonitis, tendon rupture, etc. It is contraindicated in pregnant and breastfeeding women, and is contraindicated in people with known hypersensitivity to moxifloxacin, other quinolones. There are many causes of lumbosacral pain, lumbosacral pain, it is recommended to consult a doctor in a timely manner, under the guidance of the doctor combined with the relevant examination to determine the cause of the cause of the treatment given to the cause of the problem, do not use their own medication, so as not to delay the condition.