The swelling of the hands in the morning can be caused by the following reasons: 1, cervical spondylosis, when severe cervical spondylosis compresses the nerve roots on both sides, there can be plant nerve dysfunction, and the symptoms of second-hand swelling after waking up in the morning, then the cervical spine X-ray, CT and MRI should be examined to diagnose; 2, rheumatoid, rheumatoid can often involve the hands and joints bilaterally, resulting in swelling of the hands and joint pain after waking up in the morning; 3, ankylosing spondylitis, ankylosing spondylitis can lead to swelling of the hands after waking up in the morning. This can be accompanied by morning stiffness and pain in the sacroiliac joints and spine, which can involve the entire spine, and should be checked early with X-rays of the sacroiliac joints and lumbar spine, MRI of the lumbar spine and blood tests for early diagnosis and early treatment.