Patients who stay up late for a long time may have abnormal liver function, mainly in the form of elevated transaminases, but also in the form of elevated bilirubin, glutamyl transpeptidase and other related indicators, although the magnitude of these indicators is generally not very large. According to Chinese medicine, the best time for liver detoxification is from 11:00 p.m. to 3:00 a.m. If you are still not in a state of sleep, the liver’s detoxification function will drop significantly, causing toxic substances to accumulate in the liver, thus causing certain effects on liver function. Current research has also found that even if sufficient sleep is given after a late night, it may not alleviate the effects on liver function. It should be noted, however, that if there is a significant increase in liver function indicators, it may not only be caused by staying up late, but also by liver disease, so the cause should be further specified. In addition, for people who stay up late, if they improve their sleep, liver function can gradually return to normal.